منابع مشابه
Effect of Chromium on Certain Aspects of Cellular Toxicity
Introduction: The impact of chromium exposure was studied on liver, kidney, testis, spleen, cerebrum and cerebellum of male Wistar rats (80-100 g body weight). Material & Method: It was observed that treatments of rats with chromium (i.p. at a dose of 0.8 mg / 100 g body weight per day) for a period of 28 days caused significant increase in chromium content while declining the body weight a...
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Seeds of the castor bean plant Ricinuscommunis L (CB) contain ricin toxin (RT), one of the most poisonous naturally-occurring substances known. Ricin toxin, a water-soluble glycoprotein that does not partition into the oil extract, is a ribosome-inactivating toxin composed of two chains, labeled A and B. Severity of the toxicity varies depending on the route of exposure to the toxin. Inhalation...
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C O N T E N T S I N T R O D U C T I O N . . 117 A L U M I N I U M M E T A B O L I S M . . 118 . 119 Absorption . . 119 Excretion . . 120 Tissue accumulation . . 121 P A R E N T E R A L A D M I N I S T R A T I O N . . . 122 Intravascular administration . . 122 Intraperitoneal administration . . 124 Subcutaneous administration . . . 124 Intramuscular administration. . . 124 T I S S U E E F F E C ...
متن کاملDrug Toxicity
Physicians prescribe drugs to prevent or treat disease. Those same drugs can be toxic to certain patients, however, because of genetic predisposition, nonselective action, or inappropriate use or administration of the drug. The United States Food and Drug Administration (FDA) spends a significant portion of its $1 trillion budget to ensure that new drugs are not overtly or unnecessarily dangero...
متن کاملSub Acute Toxicity of Aceclofenac Drug in Albino Rat
Introduction: Nonsteroidal anti-inflammatory drugs are the most commonly used drugs to reduce pain and inflammation. Aceclofenac is a newer derivative of diclofenac with less gastrointestinal complications. The objective of the present study was to evaluate the toxicity profile of sustain release aceclofenac injection in rats at three dose levels, ranging from 2 to 10 mg/kg body weight. Mater...
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ژورنال
عنوان ژورنال: Journal of the Royal Society of Medicine
سال: 1979
ISSN: 0141-0768,1758-1095
DOI: 10.1177/014107687907200219